Niners Coach's "Saved by the Bell" Cameo Resurfaces

If you're wondering what kind of inspirational oration the San Francisco 49ers might hear from Coach Jim Harbaugh during Sunday's Super Bowl, an old episode of "Saved by the Bell" may offer some clues.

In 1996, Harbaugh was coming off the best season of his career. Though he was only 7-5 as the Colts' starting QB that season, he led the league in passer rating, besting the likes of Brett Favre, Troy Aikman, Steve Young and Dan Marino, and was named to the Pro Bowl.

But perhaps the greatest honor conferred upon Harbaugh was a guest appearance as himself on "Saved by the Bell: The New Class." Watching the clip, one is awed by Harbaugh's perfect hair, the blazer over the mock turtleneck and the razor-sharp writing.

In it, Harbaugh is Screech's cousin, stopping by for lunch and to give Screech's friend Eric a pep talk and, ultimately, some help with a school project.

"Screech, is that you? I didn?t recognize you under all those muscles," Harbaugh says in greeting his cousin, eliciting a roar of laugh track.

Eric and his friends were supposed to do a project for Mr. Dewey about what it means to be a hero, but because of Eric, all three of them are facing an F. However, Harbaugh steps in at the 11th hour to explain to their class what heroism really is:

"Being a hero isn?t about what you do out there on the field. It's about who you are--in here," Harbaugh explained as he put his hand over his heart. "It's about helping your friends, your school and your community."

As luck would have, the teacher, Mr. Dewey, is an Indianapolis native, and Harbaugh is his hero. Dewey is so impressed with Harbaugh's speech he gives all the kids an A. It's a chain of events driven by a demented sense of morality, offering an utterly indecipherable lesson about who knows what.

Jim also had a cameo on the HBO?series "Arli$$," and appeared alongside fellow NFL stars Terry Bradshaw, Carl Banks and Ken Norton Jr. in an episode of "The Adventures of Brisco County." Harbaugh's brother John, coach of the Baltimore Ravens, has never had an acting career.

Advantage:?Niners.

The next time someone tries to tell you how terrible TV has gotten, let Harbaugh's "Saved by the Bell" appearance stand as a reminder of how far the medium has come.

Source: http://feeds.nbcchicago.com/click.phdo?i=4e157a3f8572706bdea88c68dbb37c34

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Cultural evolution changes bird song

Jan. 29, 2013 ? Thanks to cultural evolution, male Savannah sparrows are changing their tune, partly to attract "the ladies."

According to a study of more than 30 years of Savannah sparrows recordings, the birds are singing distinctly different songs today than their ancestors did 30 years ago -- changes passed along generation to generation, according to a new study by University of Guelph researchers.

Integrative biology professors Ryan Norris and Amy Newman, in collaboration with researchers at Bowdoin College and Williams College in the U.S., analyzed the songs of male Savannah sparrows (Passerculus sandwichiensis) recorded over three decades, and found that the songs had changed distinctly from 1980 to 2011.

"The change is the result of cultural transmission of different song elements through many generations," said Norris.

Norris added that the change in tune resembles changes in word choice and language among humans.

"If you listen to how people used to talk in the 1890s and how we talk today, you would notice major differences, and this is the result of shifts in culture or the popularity of certain forms," he said. "The change in sparrow songs over time has occurred much the same way"

The sparrows, which live on Kent Island, N.B., in the Bay of Fundy, can generally sing only one song type that consists of several parts. Male sparrows learn that song early in their first year and continue to sing the same tune for the rest of their lives.

"Young male sparrows learn their songs from the birds around them," said Norris. "It may be their fathers, or it could be other older male birds that live nearby."

Each male sparrow has his own unique sound, added Newman.

"While the island's sparrows all sing a characteristic 'savannah sparrow song,' with the same verses and sound similar, there are distinct differences between each bird," she said. "Essentially, it is like karaoke versions of popular songs. It is the rise and fall in popular cover versions that has changed over time."

The research team found that, in general, each song has three primary elements. The first identifies the bird as a Savannah sparrow, the second identifies which individual is singing, and the third component is used by females to assess males.

Using sonograms recorded from singing males each breeding season, the researchers determined that, while the introductory notes had stayed generally consistent for the last 30 years, the sparrows had added a series of clicks to the middle of their songs. The birds had also changed the ending trill: once long and high-frequency, it is now shorter and low-frequency.

"We found that the ending trill of the song has become shorter, likely because female sparrows preferred this, because males with shorter trills had higher reproductive success," Norris said.

Kent Island has been home to the Bowdoin Scientific Station since it was donated by J. Sterling Rockefeller in 1932, and the birds have been recorded since the 1980s. Individual birds are also monitored throughout their lifetime.

"We know the identity and history of every single sparrow in the study population" said Norris, who has led the project with Newman since 2009. "To have 30 years of recordings is very rare, and it was definitely surprising to see such drastic changes."

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The above story is reprinted from materials provided by University of Guelph.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Heather Williams, Iris I. Levin, D. Ryan Norris, Amy E.M. Newman, Nathaniel T. Wheelwright. Three decades of cultural evolution in Savannah sparrow songs. Animal Behaviour, 2013; 85 (1): 213 DOI: 10.1016/j.anbehav.2012.10.028

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/LwCj0OG8ALE/130129121937.htm

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New insights into managing our water resources

Public release date: 29-Jan-2013
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Contact: Anne Rahilly
arahilly@unimelb.edu.au
61-390-355-380
University of Melbourne

Dr Tim Peterson, from the School of Engineering at the University of Melbourne has offered new theories that will lead to a deeper knowledge of how water catchments behave during wet and dry years. His research was published recently in the leading international hydrology journal "Water Resources Research" and was selected by the American Geophysical Union as a highlight of the society's 13 international journals.

Dr Peterson's work shows that some catchments have a finite resilience to wet and dry years because they have two steady states. The traditionally held view is that water catchments have only one steady state.

A steady state can be considered as how a catchment behaves after a disturbance like a wet year. Traditionally, hydrology has assumed that no matter how wet a year is, once the rain goes back to the average then the stream flow and water table will return to what they were before the wet year. Tim's work shows that in some catchments, after a wet year the stream flow and water table can return to a very different value. His theories explain how catchments switch between these steady states and how the catchment's resilience can be measured.

"Understanding responses and how water catchments react and recover from disturbances will allow better prioritising of investment and more informed decision making about water resourcing" said Dr Peterson.

Dr Peterson concludes we should not assume that water catchments always return to the way they once were after a major disturbance. "Major state and federal agencies are working with us to use these new theories. Together, we are coming closer to understanding which catchments have multiple steady states and how they can be managed."

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 29-Jan-2013
[ | E-mail | Share ]

Contact: Anne Rahilly
arahilly@unimelb.edu.au
61-390-355-380
University of Melbourne

Dr Tim Peterson, from the School of Engineering at the University of Melbourne has offered new theories that will lead to a deeper knowledge of how water catchments behave during wet and dry years. His research was published recently in the leading international hydrology journal "Water Resources Research" and was selected by the American Geophysical Union as a highlight of the society's 13 international journals.

Dr Peterson's work shows that some catchments have a finite resilience to wet and dry years because they have two steady states. The traditionally held view is that water catchments have only one steady state.

A steady state can be considered as how a catchment behaves after a disturbance like a wet year. Traditionally, hydrology has assumed that no matter how wet a year is, once the rain goes back to the average then the stream flow and water table will return to what they were before the wet year. Tim's work shows that in some catchments, after a wet year the stream flow and water table can return to a very different value. His theories explain how catchments switch between these steady states and how the catchment's resilience can be measured.

"Understanding responses and how water catchments react and recover from disturbances will allow better prioritising of investment and more informed decision making about water resourcing" said Dr Peterson.

Dr Peterson concludes we should not assume that water catchments always return to the way they once were after a major disturbance. "Major state and federal agencies are working with us to use these new theories. Together, we are coming closer to understanding which catchments have multiple steady states and how they can be managed."

###

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-01/uom-nii_1012913.php

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The Mystery of Curry

Indian chicken jalfrezi curry. The original curry predates Europeans? presence in India by about 4,000 years.

Photograph by Joe Gough/iStockphoto/Thinkstock.

What is curry? Today, the word describes a bewildering number of spicy vegetable and meat stews from places as far-flung as the Indian subcontinent, the South Pacific, and the Caribbean Islands. There is little agreement about what actually constitutes a curry. And, until recently, how and when curry first appeared was a culinary mystery as well.

The term likely derives from kari, the word for sauce in Tamil, a South-Indian language. Perplexed by that region?s wide variety of savory dishes, 17^th-century British traders lumped them all under the term curry. ?A curry, as the Brits defined it, might be a m?lange of onion, ginger, turmeric, garlic, pepper, chilies, coriander, cumin, and other spices cooked with shellfish, meat, or vegetables.

Those curries, like the curries we know today, were the byproduct of more than a millennium of trade between the Indian subcontinent and other parts of Asia, which provided new ingredients to spice up traditional Indian stews. After the year 1000, Muslims brought their own cooking traditions from the west, including heavy use of meat, while Indian traders carried home new and exotic spices like cloves from Southeast Asia. And when the Portuguese built up their trading centers on the west coast of India in the 16^th century, they threw chilies from the New World into the pot. (Your spicy vindaloo may sound like Hindi, but actually the word derives from the Portuguese terms for its original central ingredients: wine and garlic.)

But the original curry predates Europeans? presence in India by about 4,000 years. Villagers living at the height of the Indus civilization used three key curry ingredients?ginger, garlic, and turmeric?in their cooking. This proto-curry, in fact, was eaten long before Arab, Chinese, Indian, and European traders plied the oceans in the past thousand years.

You may be wondering how on earth anyone can know what people were cooking 4,500 years ago. While the ancients left behind plenty of broken pots and mud-brick house foundations, they generally didn?t leave us their recipes. And foodstuffs, unlike pots, rapidly decay.

But thanks to technological advances, scientists can identify minute quantities of plant remains left behind by meals cooked thousands of years ago. It is no easy task; researchers must gather crumbling skeletons and find ancient dirty dishes before using powerful laboratory microscopes to pinpoint the ingredients of ancient meals. But the effort is paying off, in the form of evidence that curry may be far, far older than previously thought.

The Indus society began to flourish around the same time that the ancient Egyptians built their pyramids and Mesopotamians constructed the first great cities in today?s Iraq. Though less well known than its more famous cousins to the West, the Indus civilization boasted a half-dozen large and carefully planned urban centers with sophisticated water and sewage systems unmatched until Roman times. During its peak, between 2500 B.C. and 1800 B.C., the Indus dominated a land area larger than either ancient Egypt or Mesopotamia, covering much of today?s Pakistan and most of western India, as far west as the Iranian coast, as far north as Afghanistan, and as far east as the suburbs of New Delhi. But unlike the hieroglyphic and cuneiform writing of the Egyptian and Mesopotamian scribes, the strange symbols left behind by their Indus counterparts has not yet been deciphered by today?s scholars. Deciphering their food traditions has, until recently, been equally challenging.

Archaeologists have long known how to spot some ancient leftovers. The biggest breakthrough came in the 1960s, when excavators began to drop soil from their sites?particularly from places where food likely was prepared?onto mesh screens. The scientists then washed the earth away with water, leaving behind little bits of stone, animal bones, and tiny seeds of wheat, barley, millets, and beans. This flotation method allowed scientists to piece together a rough picture of an ancient diet. ?But spices are absent in macro-botanical record,? says archaeologist Arunima Kashyap at the University of Washington at Vancouver, who, along with Steve Weber, made the recent proto-curry discovery.

Source: http://feeds.slate.com/click.phdo?i=72c404ed7edee60fe88ca3321881ffec

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'Hansel & Gretel' Tops Box Office With Modest $19 Million

Ensemble comedy 'Movie 43' flops, collecting just $5 million during its first weekend.
By Ryan J. Downey

Jeremy Renner in "Hansel & Gretel: Witch Hunters"
Photo: Paramount Pictures

Source: http://www.mtv.com/news/articles/1700866/hansel-and-gretel-box-office-weekend.jhtml

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Explosion ? Iran, Province of Qom - Family Survival Protocol

(WARNING! This is information absolute not confirmed!) An explosion deep within Iran?s Fordow nuclear facility has destroyed much of the installation and trapped about 240 personnel deep underground, according to a former intelligence officer of the Islamic regime. The previously secret nuclear site has become a center for Iran?s nuclear activity because of the 2,700 centrifuges enriching uranium to the 20-percent level. A further enrichment to weapons grade would take only weeks, experts say. The level of enrichment has been a major concern to Israeli officials, and Prime Minister Benjamin Netanyahu repeatedly has warned about the 20-percent enriched stockpile. The explosion occurred Monday, the day before Israeli elections weakened Netanyahu?s political control. Iran, to avoid alarm, had converted part of the stockpile to fuel plates for use in the Tehran Research Reactor. However, days after the recent failed talks with the International Atomic Energy Agency, Iranian officials announced the enrichment process will not stop even ?for a moment.?

The regime?s uranium enrichment process takes place at two known sites: the Natanz facility with more than 10,000 centrifuges and Fordow with more than 2,700. The regime currently has enough low-grade (3.5 percent) uranium stockpiled for six nuclear bombs if further enriched. However, more time is needed for conversion of the low-grade uranium than what would be needed for a stockpile at 20 percent. It takes 225 kilograms of enriched uranium at the 20-percent level to further enrich to the 90-percent level for one nuclear bomb. According to a source in the security forces protecting Fordow, an explosion on Monday at 11:30 a.m. Tehran time rocked the site, which is buried deep under a mountain and immune not only to airstrikes but to most bunker-buster bombs. The report of the blast came via Hamidreza Zakeri, formerly with the Islamic regime?s Ministry of Intelligence and National Security, The blast shook facilities within a radius of three miles. Security forces have enforced a no-traffic radius of 15 miles, and the Tehran-Qom highway was shut down for several hours after the blast, the source said. As of Wednesday afternoon, rescue workers had failed to reach the trapped personnel.

The site, about 300 feet under a mountain, had two elevators which now are out of commission. One elevator descended about 240 feet and was used to reach centrifuge chambers. The other went to the bottom to carry heavy equipment and transfer uranium hexafluoride. One emergency staircase reaches the bottom of the site and another one was not complete. The source said the emergency exit southwest of the site is unreachable. The regime believes the blast was sabotage and the explosives could have reached the area disguised as equipment or in the uranium hexafluoride stock transferred to the site, the source said. The explosion occurred at the third centrifuge chambers, with the high-grade enriched uranium reserves below them. The information was passed on to U.S. officials but has not been verified or denied by the regime or other sources within the regime. Though the news of the explosion has not been independently verified, other sources previously have provided WND with information on plans for covert operations against Iran?s nuclear facilities as an option before going to war. The hope is to avoid a larger-scale conflict. Israel, the U.S. and other allies already have concluded the Islamic regime has crossed its red line in its quest for nuclear weapons, other sources have said.

Source: http://familysurvivalprotocol.com/2013/01/28/explosion-iranprovince-of-qom-fordow-nuclear-facility/

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5 large peculiar effectiveness of green tea | Health and Fitness Tips ...

The effectiveness of green tea, along the following:

1, Weight-loss reduce fat: green tea rich theophylline and caffeine, many effects via activation of protein kinase and triglyceride lipase to reduce the accumulation of fat cells, and thus arrive slimming effectiveness.

2, Prevention of dental caries, clear bad breath: green tea rich fluorinated meantime catechins can inhibit the effect of cariogenic bacteria, reducing plaque and periodontitis onset. Tea contains tannic acid, has a sterilizing effect, crumbs of food residue can hinder the proliferation of bacteria, it can be useful to prevent bad breath.

3, Anti-cancer: green tea inhibit the effect of certain cancers, but its principles are limited inference time. Episodes of anti-cancer, more tea must be the effect of positive encouragement.

4, Whitening and anti-UV effect: professors found in animal studies, green tea catechins resistant to UV-B induced skin cancer.

5, Improve indigestion status: discussion show, green tea can help improve the situation of indigestion, for example by the bacteria causing acute diarrhea, drink a little green tea to alleviate the condition.

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  1. Barley for containing a variety of vitamins and minerals can promote metabolism and reduce the burden of gastrointestinal function. Frail patients can be used for replenishing food; 2. Regular ...
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  1.Garlic: Garlic contains allicin, fasting to eat garlic, will gastric mucosa, intestinal wall caused by strong stimulation, can lead to gastrointestinal spasm and cramps. 2.Cold drinks: Fastin...
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  1, Nuts Rich in unsaturated fatty acids in nuts, olive oil can provide a similar effect, they concentrated a lot of vitamins, minerals and other phytochemicals alkaloids, contain anti-oxidants. 2,...
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This entry was posted on Sunday, January 27th, 2013 and is filed under Health Tips. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Source: http://www.hhtip.com/5-large-peculiar-effectiveness-of-green-tea/

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Researchers break million-core supercomputer barrier

Jan. 28, 2013 ? Stanford Engineering's Center for Turbulence Research (CTR) has set a new record in computational science by successfully using a supercomputer with more than one million computing cores to solve a complex fluid dynamics problem -- the prediction of noise generated by a supersonic jet engine.

Joseph Nichols, a research associate in the center, worked on the newly installed Sequoia IBM Bluegene/Q system at Lawrence Livermore National Laboratories (LLNL) funded by the Advanced Simulation and Computing (ASC) Program of the National Nuclear Security Administration (NNSA). Sequoia once topped list of the world's most powerful supercomputers, boasting 1,572,864 compute cores (processors) and 1.6 petabytes of memory connected by a high-speed five-dimensional torus interconnect.

Because of Sequoia's impressive numbers of cores, Nichols was able to show for the first time that million-core fluid dynamics simulations are possible -- and also to contribute to research aimed at designing quieter aircraft engines.

The physics of noise

The exhausts of high-performance aircraft at takeoff and landing are among the most powerful human-made sources of noise. For ground crews, even for those wearing the most advanced hearing protection available, this creates an acoustically hazardous environment. To the communities surrounding airports, such noise is a major annoyance and a drag on property values.

Understandably, engineers are keen to design new and better aircraft engines that are quieter than their predecessors. New nozzle shapes, for instance, can reduce jet noise at its source, resulting in quieter aircraft.

Predictive simulations -- advanced computer models -- aid in such designs. These complex simulations allow scientists to peer inside and measure processes occurring within the harsh exhaust environment that is otherwise inaccessible to experimental equipment. The data gleaned from these simulations are driving computation-based scientific discovery as researchers uncover the physics of noise.

More cores, more challenges

"Computational fluid dynamics (CFD) simulations, like the one Nichols solved, are incredibly complex. Only recently, with the advent of massive supercomputers boasting hundreds of thousands of computing cores, have engineers been able to model jet engines and the noise they produce with accuracy and speed," said Parviz Moin, the Franklin M. and Caroline P. Johnson Professor in the School of Engineering and Director of CTR.

CFD simulations test all aspects of a supercomputer. The waves propagating throughout the simulation require a carefully orchestrated balance between computation, memory and communication. Supercomputers like Sequoia divvy up the complex math into smaller parts so they can be computed simultaneously. The more cores you have, the faster and more complex the calculations can be.

And yet, despite the additional computing horsepower, the difficulty of the calculations only becomes more challenging with more cores. At the one-million-core level, previously innocuous parts of the computer code can suddenly become bottlenecks.

Ironing out the wrinkles

Over the past few weeks, Stanford researchers and LLNL computing staff have been working closely to iron out these last few wrinkles. This week, they were glued to their terminals during the first "full-system scaling" to see whether initial runs would achieve stable run-time performance. They watched eagerly as the first CFD simulation passed through initialization then thrilled as the code performance continued to scale up to and beyond the all-important one-million-core threshold, and as the time-to-solution declined dramatically.

"These runs represent at least an order-of-magnitude increase in computational power over the largest simulations performed at the Center for Turbulence Research previously," said Nichols "The implications for predictive science are mind-boggling."

A homecoming

The current simulations were a homecoming of sorts for Nichols. He was inspired to pursue a career in supercomputing as a high-school student when he attended a two-week summer program at Lawrence Livermore computing facility in 1994 sponsored by the Department of Energy. Back then he worked on the Cray Y-MP, one of the fastest supercomputers of its time.

"Sequoia is approximately 10 million times more powerful than that machine," Nichols noted.

The Stanford ties go deeper still. The computer code used in this study is named CharLES and was developed by former Stanford senior research associate, Frank Ham. This code utilizes unstructured meshes to simulate turbulent flow in the presence of complicated geometry.

In addition to jet noise simulations, Stanford researchers in the Predictive Science Academic Alliance Program (PSAAP), sponsored by the Department of Energy, are using the CharLES code to investigate advanced-concept scramjet propulsion systems used in hypersonic flight (with video) -- flight at many times the speed of sound -- and to simulate the turbulent flow over an entire airplane wing.

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The above story is reprinted from materials provided by Stanford School of Engineering. The original article was written by Andrew Myers.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/ms7cX5a1IAs/130128104628.htm

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Stem cells aid recovery from stroke

Public release date: 27-Jan-2013
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Contact: Hilary Glover
hilary.glover@biomedcentral.com
44-020-319-22370
BioMed Central

Stem cells from bone marrow or fat improve recovery after stroke in rats, finds a study published in BioMed Central's open access journal Stem Cell Research & Therapy. Treatment with stem cells improved the amount of brain and nerve repair and the ability of the animals to complete behavioural tasks.

Stem cell therapy holds promise for patients but there are many questions which need to be answered, regarding treatment protocols and which cell types to use. This research attempts to address some of these questions.

Rats were treated intravenously with stem cells or saline 30 minutes after a stroke. At 24 hours after stroke the stem cell treated rats showed a better functional recovery. By two weeks these animals had near normal scores in the tests. This improvement was seen even though the stem cells did not appear to migrate to the damaged area of brain. The treated rats also had higher levels of biomarkers implicated in brain repair including, the growth factor VEGF.

A positive result was seen for both fat (adipose) and bone-marrow derived stem cells. Dr Exuperio Dez-Tejedor from La Paz University Hospital, explained, "Improved recovery was seen regardless of origin of the stem cells, which may increase the usefulness of this treatment in human trials. Adipose-derived cells in particular are abundant and easy to collect without invasive surgery."

###

Media Contact

Dr Hilary Glover
Scientific Press Officer, BioMed Central
Mob: 44-778-698-1967

Notes

1. Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
Mara Gutirrez-Fernndez, Berta Rodrguez-Frutos, Jaime Ramos-Cejudo, M Teresa Vallejo-Cremades, Blanca Fuentes, Sebastin Cerdn and Exuperio Dez-Tejedor
Stem Cell Research & Therapy (in press)

Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.

Article citation and URL available on request on the day of publication.

2. Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.

3. BioMed Central is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector. @BioMedCentral

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 27-Jan-2013
[ | E-mail | Share ]

Contact: Hilary Glover
hilary.glover@biomedcentral.com
44-020-319-22370
BioMed Central

Stem cells from bone marrow or fat improve recovery after stroke in rats, finds a study published in BioMed Central's open access journal Stem Cell Research & Therapy. Treatment with stem cells improved the amount of brain and nerve repair and the ability of the animals to complete behavioural tasks.

Stem cell therapy holds promise for patients but there are many questions which need to be answered, regarding treatment protocols and which cell types to use. This research attempts to address some of these questions.

Rats were treated intravenously with stem cells or saline 30 minutes after a stroke. At 24 hours after stroke the stem cell treated rats showed a better functional recovery. By two weeks these animals had near normal scores in the tests. This improvement was seen even though the stem cells did not appear to migrate to the damaged area of brain. The treated rats also had higher levels of biomarkers implicated in brain repair including, the growth factor VEGF.

A positive result was seen for both fat (adipose) and bone-marrow derived stem cells. Dr Exuperio Dez-Tejedor from La Paz University Hospital, explained, "Improved recovery was seen regardless of origin of the stem cells, which may increase the usefulness of this treatment in human trials. Adipose-derived cells in particular are abundant and easy to collect without invasive surgery."

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Media Contact

Dr Hilary Glover
Scientific Press Officer, BioMed Central
Mob: 44-778-698-1967

Notes

1. Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
Mara Gutirrez-Fernndez, Berta Rodrguez-Frutos, Jaime Ramos-Cejudo, M Teresa Vallejo-Cremades, Blanca Fuentes, Sebastin Cerdn and Exuperio Dez-Tejedor
Stem Cell Research & Therapy (in press)

Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.

Article citation and URL available on request on the day of publication.

2. Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.

3. BioMed Central is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector. @BioMedCentral

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-01/bc-sca012513.php

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The Estate Condo by Lougheed House & Ranchmans Club Condo ...

?The Estate? Condo was built in 1980 and is located at 720 13th Ave SW, Calgary, right next door to the world famous Ranchmen?s Club and across the street from Lougheed House, in the Community of Connaught.? It is ?The Estate? is? registered on Condominium Plan 8211330.? It comprises a 27-Story high-rise tower adjoining the Ranchmen?s Club and also a 7-story Low-Rise structure to the west which houses a number of town-homes and low-rise condominium units.

The homes in ?The Estate? range in size from the smallest being 882 sq. ft to the two 3175 square foot Penthouse units on the 27th floor.? The average size of the units is about 1600 sq. ft.? ?The Estate? mirrors the traditions, style and finishing?s of the adjoining Ranchman?s Club and the visitor is greeted by a 24/7 full service concierge who watches over the pristine surroundings and takes care of the ?little things? for you.

Mel Buyer ? Day Concierge Extraordinaire at ?The Estate?

The atmosphere is non-pretentious and those that have made ?The Estate? their home are generally not scuttling about, type A over-achievers.? They have already made their mark in life and are now enjoying the fruits of their labour in the manner to which they have become accustomed.? The units in the high-rise tower of ?The Estate? have no balconies, rendering them relatively dust free.? The floor plans are open and spacious with interesting angles which are perfect for incredible furniture layouts to suite your lifestyle, while still feeling comfortable and cozy.

?The Estate? Low-Rise condominium complex houses four two-story town homes and the rest are apartment style condominiums. Many of these homes have large balconies and large terraces.

Condo fees in ?The Estate? usually range between $1000 and $3000 and as of the date of this review.? If this concerns you in the least, then ?The Estate? is definitely not for you. ?The Estate? is professionally managed by Twylla Walker.

?Amenities in ?The Estate?

• On-Site Manager (5th Floor)
• Swimming Pool with kitchenette/wet bar ? May be reserved for private functions. (5th Floor)
• Roof top Patio between the two buildings (5th Floor)
• Whirl Pool
• Exercise Room (5th Floor)
• Garbage Chutes (Undetectable)
• 9? Ceilings
• Large Terrace Patios on many of the low-rise units
• Central Air Conditioning.

?

Wet Bar in ?The Estate? Swimming Pool Recreation Room

Parking in ?The Estate?

• 4 Levels of secured, assigned underground parking. Two levels up, and two levels down from the main floor.? Many suites have two parking stalls
• 10 underground secured visitor stalls

Inclusions at ?The Estate?

• Heat
• Water/Sewer
• Electricity
• Cable & Internet

Restrictions

To arrange for a private showing, or offer for sale any units for sale in ?The Estate? call me to take care of the details.

Mike Leibel - 403-204-1111

New music review: Elephant Stone (Hidden Pony) | Montreal Gazette

Photo courtesy of Mauvaise Influence

With its self-titled sophomore release, Montreal?s Elephant Stone neatly sidestep the ?difficult second album? syndrome and deliver instead what is more like a mission statement.

Not that the group?s debut, The Seven Seas, released in 2009, was tentative. Stylistically varied, smartly arranged and melodically arresting, it grabbed enough acclaim to become a Polaris Prize nominee.

By comparison, the new disc is darker and denser, inviting attentive listens at serious volume to crack the surface. and once you really hear the harsh beauty at this album?s heart, it becomes clear that this is a stone-cold psychedelic marvel.

As usual, the group?s leader and songwriter, Rishi Dhir, walks the parallel paths of jangly pop and lava-lamp anarchy ? aided, in no small way, by guitarist Gabriel Lambert, who sometimes goes all Jorma Kaukonen with howling solos and peals of sonic texture, notably on the assertive opener Setting Sun, which could fit on a neo-psych Nuggets anthology.

Lambert?s greatest moment, and the album?s, comes on the almost nine-minute explosion The Sea of Your Mind, which tosses in everything but the kitchen sink: phased vocals, a sitar break by Dhir, a no-nonsense riff and swelling walls of roaring guitar. In your imagination, you can see the liquid lightshow projections behind the band asthey keep it going live past the half-hour mark.

A Silent Moment is the disc?s other standout track, with the vocals of classical singer Pandit Vinay Bhide sharing space with Dhir?s bass line time-traveling from somewhere around Revolver.

When psychedelic music first became part of the rock landscape, artists generally tempered their experimental ambitions with a nod to the Top 40 charts, and this album follows that time-worn pattern. The Be My Baby backbeat in Hold Onto Your Soul and the chiming catchiness of Love the Sinner, Hate the Sin are as representative of this strobe-light voyage as the backwards guitar that creates Heavy Moon?s hypnotic drone.

The spirit of `67 lives on in these tracks. But then, it never really went away, did it?

Rating: **** and 1/2

Podworthy: The Sea of Your Mind

Elephant Stone will be available Feb. 5. Elephant Stone performs Feb. 15 at 9:30 p.m. at Divan Orange, 4234 St. Laurent Blvd. Tickets cost $10, plus a $2 charge if purchased in advance. Go to http://indiemontreal.ca/elephant-stone-w-guests.

Here?s the video for Heavy Moon:

For something on the poppier side of the band?s repertoire, this is Love the Sinner, Hate the Sin:

Click here to check out the band?s Web site.

Elephant Stone performs Feb. 15 at 9:30 p.m. at Divan Orange, 4234 St. Laurent Blvd. Tickets cost $10, plus a $2 charge if purchased in advance. Go to http://indiemontreal.ca/elephant-stone-w-guests.

And last, but far from least, watch for our feature interview with Rishi Dhir on Jan. 29 in the Gazette?s print edition and at montrealgazette.com.

Bernard Perusse

Twitter: @bernieperusse

Source: http://blogs.montrealgazette.com/2013/01/26/new-music-review-elephant-stone-hidden-pony/

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Illinois to allow immigrants to get licenses

SPRINGFIELD, Ill. (AP) ? Illinois is the fourth state to allow illegal immigrants to obtain a driver's license with a new law signed by the governor.

Democratic Gov. Pat Quinn signed the legislation Sunday surrounded by hundreds of supporters who say the measure will make Illinois' roads safer and expand opportunities for illegal immigrants.

Quinn says people need a way to get to work, drive to the doctor and drive their children to school. Chicago Mayor Rahm Emanuel says the new law should serve as a model for the nation.

New Mexico and Washington both issue licenses to undocumented immigrants, while Utah issues permits.

Illinois officials say the dissemination of the temporary licenses is expected to begin in November.

The legislation was billed as a public safety measure and had bipartisan support.

Source: http://news.yahoo.com/illinois-allow-immigrants-licenses-221430757.html

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Hookup Culture: Why Millennials Struggle With Attachment and ...

It turns out that there are ?Strings Attached? in our ?Friends with Benefits? Culture

Historic Christian morality and modern neuroscience have come to the same conclusion: sex forms a nearly inseparable?bond. ?

by Mike Friesen?? Launch Ministry

What is going on with Millennials and their sexuality? Friends with Benefits? No Strings Attached Relationships? Hooking up?

What we see in the Millennial generation is a generation that didn?t want to see the dysfunctional marriages that they themselves lived with when they were growing up and yet they still wanted to sustain and gratify their sexual urges (hence, these uncommitted relationships). My generation is having a hard time forming attachments with other people.

Erikson and Freud more Kutcher and Portman

You can blame it on Hollywood. Movies like ?Friends with Benefits? with Justin Timberlake and Mila Kunis or ?No Strings Attached? with Ashton Kutcher and Natalie Portman certainly chronicle the issue, but they hardly caused it. You could blame it on a culture that is built around instant gratification. You could even say that it is our ultimate desire that we just want to do what other people are doing so that we aren?t a social oddity.

Ultimately, I believe it comes down to an identity problem.?No matter how we go through life we will assert our imprint on the world. Even social disengagement is a form of social engagement. How we interact with the world stems from a fundamental understanding of who we think we are. So in my sexual relationships, I have sex (or don?t have sex) with those based on how I understand myself and how I understand myself through others.

One of the most renowned 20th century psychologists Erik Erikson noted that the age in which we are supposed to be developing meaningful and bonding relationships happens between 18-30 (the age of the current Millennial relationships). Erikson believed, and I believe rightly, that it takes two whole people to bond and create whole relationships. It isn?t rocket science that broken people tend to create two types of social reactions when relationships are imposed upon them: codependent relationships or retreating into isolation.

Neuroscience and Morality?

As Christians we believe that when we engage in sexual activity that there is a bond that is inseparable. Neuroscience has come to the same conclusion. When people have sex, several chemicals in their brain are released: one is oxytocin and another is dopamine. Oxytocin is the bonding chemical. When we have sex with someone we are supposed to be bonded to this person.

The more bonds we form with others, and these relationships are torn apart or disengaged, the more we struggle to bond with another. Dopamine is the feel good chemical. The more dopamine is released in our brain, the more we become attached to it. This is how sexual addictions are created. Sigmund Freud also called this engagement where sexual activity is used as a form to merely annihilate the tension we feel in our body a Death Instinct. It seems that from the Bible to neuroscience to Freud, that our sexuality outside of Eros, out of continual longing for union with a person, that our actions will lead to some form of biological or metaphysical death.

It?s Identity

All of this to bring us back to our fundamental question: Who am I? When we don?t know who we are, we won?t know what to do in our social engagements (sexual or not). Maybe our critique of the Millennial generation, my generation, comes from a poor or broken understanding of who we are. For Christians, we are called to help people understand who they are in Christ (as the beloved). If we are not Christians, how do we invite people into wholeness? How do we help people find themselves? How do we help people find one another?

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Mike Friesen blogs on topics related to Millennial life and spirituality for?Launch Ministry?and?Christianity for the Rest of Us.?Connect with him on?Twitter?and?Facebook.

See Also

Are Millennials Creating a New Religion? by Mike Friesen

The Zacchaeus Generation: Identity, Community, and Seeing, by Mike Friesen

How ?Boy Meets World? Reveals What My Generation Thinks About God, by Mike Friesen

Video: What South Park Teaches Us About Easter, by Mike Friesen

The Social Media Gospel: We Can?t Be Witnesses Where We?re Not Present, by Mike Friesen

The Poetry of Batman: This is how The Dark Knight Rises, by Mike Friesen

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Source: http://garydavidstratton.com/2013/01/25/hookup-culture-why-millennials-struggle-with-attachment-and-relationships/

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Feds: Disabled students must have sports

Chris Gardner / ASSOCIATED PRESS

Wheelchair athlete Tatyana McFadden, 16, races along side other runners in her first track meet along side able-bodied high school runners in Rockville, Md.

By Tracy Connor, Sr. Staff Writer, NBC News

The feds are ordering schools across the country to make "reasonable" changes to sports programs so that disabled students can play ? or else create separate teams for them.

The new guidance from the Education Department issued Friday was hailed by advocates for the disabled but denounced by a conservative think-tank that said it could cost big bucks for cash-strapped schools.

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"We think it?s huge and historic. In my opinion it could have the same effect, if properly implemented, as Title IX did for women," said Kirk Bauer, executive director of Disabled Sports USA.

Title IX required schools to offer girls and boys the same athletic opportunities and resulted in a huge uptick in female participation in school sports after it took effect 40 years ago.

The new order from the Education Department says athletics is also a civil right for the disabled and schools that don?t protect it could lose federal funding.

Under the latest rules, schools must tweak traditional programs to give qualified disabled students a shot at playing as long as they can do it without fundamentally changing the sport or giving anyone an advantage.

For instance, a visual aid instead of a starter pistol for the deaf runner would be easy to implement, while adding a fifth base to a baseball field to shorten running distances would be considered too big a change.

If alterations to a traditional team?aren't?feasible, schools must create a sports program that is open to disabled students, the order says. If there?aren't?enough students, schools should seek to create district-wide, regional or mixed-gender programs.

That part of the directive could be a huge financial burden, said Mike Petrilli, executive vice president of the Thomas B. Fordham Institute, a right-leaning educational research nonprofit.

?I?m sympathetic to the idea that kids with disabilities should be able to play sports, but this is an incredible example of executive overreach and a huge unfunded mandate,? Petrilli said.

?It?s not clear how far schools have to go. Is wheelchair basketball enough or do they need to have wheelchair tennis and other sports, too??

Bauer said such concerns are off-base, ?that schools will not be asked to have a disabled counterpart for every sport.

?It?s not going to be across the board,? he said. ?Maybe football is not the sport that is going to be integrated.?

The letter from the feds gives some examples of ways schools can be creative but it does not spell out everything.

Casey Followay, 15, of Wooster, Ohio, who races in a wheelchair alone on his track team, hopes the policy will allow him to go up against runners. ?It?s going to give me the chance to compete against kids at my level,? he told the Associated Press.

Lindsay Jones of the Council for Exceptional Children said that since disabilities are so individualized, the response to them needs to be, as well.

?I do thing you?re going to see some case-by-case lawsuits,? she said.

Ron Ingram, a spokesman for the Alabama High School Athletic Association, said he did not expect enormous changes at the school level in his state.

?We already have gone to great lengths to include students with disabilities in a way that it is not detrimental to the fundamental concept of the contest,? he said, pointing to a wrestler with no legs who racked up a 36-14 record in his senior year competing on a traditional team.

He said a wheelchair division at the state track-and-field championships has been a ?disappointment,? with not much interest. ?A majority of our special-needs students would prefer to compete in the Special Olympics,? he said.

?I think, based on what I?ve read so far, the biggest impact will just remind us all that we do need to go to great lengths to make sure all our students athletes are not discriminated against,? Ingram said.

The Associated Press contributed to this report.

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Source: http://usnews.nbcnews.com/_news/2013/01/25/16696160-disabled-students-must-be-given-sports-says-education-dept?lite

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Get In Shape for Women Presents $2,200 TADS | The Groton Line

Groton?s Teenage Anxiety and Depression Solutions (TADS) organization will receive a $2200 donation from Westford?s Get In Shape For Women studio today, the result of a six-month long community outreach program.

Get In Shape, at 142 Littleton Road, pledged to donate $100 for every new client referred by a current client. Neil Pendleton, the manager of Westford?s Get In Shape For Women, and Deb Boczenowski, a current member of GISFW and founder of TADS put the project together.

?I was thrilled when Neil told me about this membership drive because it combines two of my passions; staying in shape and helping young people in need of mental health services. Studies have shown that exercise can help to reduce ailments such as anxiety, depression, and ADD,? Boczenowski said. Exercising has been proven to release ?feel good? brain chemicals, reduce immune system chemicals, and increase body temperature which can create a calming effect (Mayo Clinic), she said.

?We teamed up with TADS because we want support our clients both in and outside of our studio,? Pendleton said. ?TADS was started by a client of ours whose son tragically passed too soon in life after having battled with anxiety and depression. We wanted to support her and other clients who live in the local communities TADS provides services in. Additionally, many of our clients are mothers of teenagers who may need help and benefit whether it be directly or indirectly from the mental health prevention and awareness services that organizations like TADS provide. I?m so glad we are able to support TADS, the Boczenowskis, and twenty-two new clients, who took their first steps towards improving their health and wellness. Our studio is a very special community of women all working toward reaching health and fitness goals.?

Teenage Anxiety and Depression Solutions (TADS) was founded in 2011 by a group of concerned citizens bound by the shared tragedy of a loved one lost to suicide. Based in Groton, their mission is to address issues of mental health issues by raising awareness, providing education, and enabling access to care. Some of TADS accomplishments have been annual training in suicide prevention curriculum for educators from across the state and providing a mental health referral service for local communities Groton, Dunstable, Ayer, and Shirley.

Source: http://www.thegrotonline.com/2013/01/26/get-in-shape-for-women-presents-2200-tads/?utm_source=rss&utm_medium=rss&utm_campaign=get-in-shape-for-women-presents-2200-tads

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Stow Is a Packing List App that Makes Sure You Don?t Leave Anything Important Behind

iPhone: Making sure you take everything you need with you on vacation or a business trip starts with a decent packing list, and Stow is an iPhone app that uses some basic information about you and the type of trip you're planning to build you the perfect list.

After downloading, the app asks you some basic questions, like whether you wear glasses or contacts, and what essential items you want to make sure you never leave home without?things like medication, specific equipment, things you can't live without. From there, you can select the type of trip you're taking, whether it's a beach vacation or a family visit, and the app will bring up a template, add your necessary items, and give you a checklist to mark off while you pack. The app even gives you the option to pack for specific types of weather you might run into on your trip.

The templates are what really makes Stow worthwhile, but if you prefer your packing lists free and on the web, previously mentioned Universal Packing List may be old, but it's still alive and kicking.

Stow ($2) | iTunes App Store via The Next Web

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/GBqKGz6pxEk/stow-is-a-packing-list-app-that-makes-sure-you-dont-leave-anything-important-behind

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Visionary Instruments intros the Robocaster MIDI hybrid guitar, we go ears-on (video)

Visionary instruments has been tinkering with the not-so-humble guitar for a long time now. The latest offering is the Robocaster MIDI guitar. As you can see from the picture above (or gallery below) the Robocaster offers some features you might not find on your average axe. Those arcade style buttons, the MPC style pad faders, touch-strips and digital whammy-bar send out MIDI data to the software of your choice. The set-up at NAMM had the Robocaster routing through Ableton Live, meaning that effects such as gating, filters -- or essentially anything -- can be lavished on your playing in real-time. The guitar is customized by hand, and make use of our good friend arduino. As Visionary Instruments has been modding guitars for a while, it's no surprise that the finish and build quality looked and felt excellent. The additional controls sit snug in the body, and are designed to be easily accessible while playing. The Robocaster, despite being hand-made, will be ready for ordering within a week or so with an estimated price somewhere around $2,799. That said, if orders or interest are sufficient, the could be scope for a full production run, coming in at a lower price. Want to make this happen? Check out the firm's website and get your order in. Just want to know how it sounds? Better get on the video after the break.

Gallery: Visionary Guitars Robocaster hands-on

Billy Steele contributed to this report.

Filed under: Misc

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/osE56mZKPYQ/

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Sony fined ?250,000 in the UK over 2011 hacking fiasco

A UK government agency has slapped Sony's wrist with a £250,000 penalty for not doing enough to protect the personal information of its customers. The fine specifically concerns the large-scale PSN hack in April 2011, which the Information Commissioner's Office (ICO) says "could have been prevented." The agency's head, David Smith, said that the security measures Sony had in place "were simply not good enough." He added that Sony trades on its technical know-how, and had access to the necessary expertise to protect itself from criminal attacks:

"There's no disguising that this is a business that should have known better."

Though the size of the fine might seem piddling for an outfit like Sony, the ICO considers it to be a "substantial" punishment, reflecting the fact that this case is "one of the most serious" that has ever been reported to it. Check out David Smith's statement and best angry teacher face in the video after the break.

Filed under: Gaming, Internet, Sony

Comments

Source: ICO

Source: http://www.engadget.com/2013/01/24/sony-fined-in-the-uk-over-hacking/

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